New method: More timely and reliable transmission of wireless sensor networks

Since sensor nodes in wireless sensor networks (WSNs) are cheap and powered by batteries, their capabilities in communication and energy supply are relatively weak and limited. The deployment of relay nodes in constructing robust network topology can significantly enhance connectivity and reduce energy consumption of WSNs. However, relay nodes are usually very expensive, thus conventional placement methods only optimize the deployment cost subject to the connectivity constraint. With a mounting of WSNs application in the field of industrial automation and smart grid, timeliness and reliability must be considered. A research group led by Prof. LIANG Wei and Prof. ZHENG Meng from Shenyang Institute of Automation (SIA) of the Chinese Academy of Sciences proposed a novel relay node placement method for WSNs which serves as a solid foundation to guarantee the real-time and reliable transmission of WSNs. They proposed for the first time a relay deployment method for WSNs in practical environment. This study was published on IEEE Transactions on Mobile Computing. In this study, the large-scale relay deployment problems are decomposed into sub-problems by levels, and shortest path tree ...

The Best Resorts in the World: 2019 Readers’ Choice Awards

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We put the top folders, fixed blades, and replaceable blades through the wringer to see which

We put the top folders, fixed blades, and replaceable blades through the wringer to see which models make the cut The knife you carry in your pocket or pack says a lot about who you are as an outdoorsman or -woman. And these days, there are more knife companies and product offerings than ever. So we gathered an array of folders, fixed blades, and replaceable blades from well-known knife makers to see how they stacked up against our battery of objective and subjective tests, with the goal of discovering which of these knives deserve to tag along on your next adventure. We settled on the three basic categories above because they are the most useful to all-around pursuits. The pocket-clip folder has largely replaced the traditional pocketknife or belt-sheath folding knife for everyday carry (EDC). They are usually slim, designed to be opened with one hand, and available in a dizzying array of blade shapes, sizes, and materials. Replaceable-edge knives have become popular because their cutting edges can be razor-thin and thus razor-sharp, and since the blade strength is supplied by the frame. Another benefit, of course, is that no sharpening is required. The trusty fixed-blade knif...

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

F508del, the most frequent mutation causing cystic fibrosis (CF), results in mistrafficking and premature degradation of the CFTR chloride channel. Small molecules named correctors may rescue F508del-CFTR and therefore represent promising drugs to target the basic defect in CF. We screened a carefully designed chemical library to find F508del-CFTR correctors. The initial active compound resulting from the primary screening underwent extensive chemical optimization. The final compound, ARN23765, showed an extremely high potency in bronchial epithelial cells from F508del homozygous patients, with an EC50 of 38 picomolar, which is more than 5000-fold lower compared to presently available corrector drugs. ARN23765 also showed high efficacy, synergy with other types of correctors, and compatibility with chronic VX-770 potentiator. Besides being a promising drug, particularly suited for drug combinations, ARN23765 represents a high-affinity probe for CFTR structure-function studies. The F508del mutation is the most frequent among patients with cystic fibrosis (CF) (1). F508del severely impairs the folding and stability of the CF transmembrane conductance regulator (CFTR) protein, a ch...

ZIDONG pump company hot sale dredging equipment for CSD500 …

China heavy duty marine sand dredge pumpThe ZN500 dredge pump is one of our hottest models for dredging industry. Pump adopt wear resistant high chrome hard metal material,much more suitable for those highly abrasive working conditions. Such as sand,gravel,mud,clay,stone and other abrasive slurries. Zidong pump company made lots of modification on it based on modern 3D mold,the pump have big flow channel and high efficiency. Wet parts are made from wear resistant high chrome hard metals,easy to use ,lower cost for maintenance. It is an ideal pumping equipment for various dredger ,widely used for sand suction,gravel dredging,land reclamation,harbor dredging,etc. Email: zdpump2@hbzdpump.comWhatsapp: +86-15830165267Skype:allenfan83Web: www.hbzdpump.com | www.cnslurrypump.com Hydroman™(A Tobee Brand) Submersible copper sewage slurry pumps are heavy duty agitator submersible slurry pumps, dredge Pumps, sand Pumps, and sludge Pumps in the Industry, capable of handling slurry, sand, gravel, solids and all kinds of sludge in diverse applications related to the dredging, construction, oil and mining industry as well as marine, energy, and industrial sectors. TJQ Submersible Slurry Pumps ...

CNC Tapping Machine Market 2020 | Worldwide Opportunities, Driving Forces, Future Potential 2024: Akira Seiki, Benign Enterprise, BRUSA & GARBOLI, CHMER

This research report is equipped with the information categorize for  CNC Tapping Machine  Market by parameters such as players, brands, regions, types and application. The report also details the information about the global market status, competition landscape, growth rate, future trends, market drivers, challenges, opportunities and porter’s forces analysis with respect to these elements. Manufacturer Detail, Akira Seiki, Benign Enterprise, BRUSA & GARBOLI, CHMER, Doosan Machine Tools, EMISSA, ERLO, FAIR FRIEND, GAMOR, KAAST Machine Tools, Kasthuri Machine Builders, Kira America, NEWAY CNC EQUIPMENT Product Type Segmentation, Pneumatic Tapping Machines, Electronic Tapping Machines, Hydraulic Tapping Machines The CNC Tapping Machine market research report has been compiled through extensive primary research through interviews, surveys, and observations of seasoned analysts and secondary research. The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and CNC Tapping Machine market participants across key points in the industry’s value chain. The report also provides exhaustive PEST analysis for all five...

Two new species of tropical “tuna” fish are now migrating further north to the South Coast

Two new species of tropical “tuna” fish are now migrating further north to the South Coast of Buzzards Bay, surprising fishermen who catch them while going after striped bass and bluefish. They are the Atlantic bonito and the false albacore found primarily in more temperate waters around Florida and from the West Indies to Brazil.             Although tuna-like in a number of ways, the bonito is from the tuna and mackerel family; the false albacore is often mistaken for a tuna, but is actually a type of mackerel.             The Massachusetts Division of Fisheries and Wildlife reports that everyone wants to jump on global warming to explain it; however, they say it could be due to a changing bait source, such as an increase in sand eels in our local waters. Experts also say there is a lot we still do not know about these species of tuna/mackerel, resulting in a lack of state fishing regulations for conservation of the species.             In appearance, the bonito has a higher profile, with eight bright blue diagonal lines across its back, as illustrated. The false albacore has smaller wavy lines on its back, but both have the same streamlined torpedo shape for robust swimming a...

Design tricks and finishing touches: Dan Gayfer Design create space for Brighton East Interior

A simple interior renovation by Dan Gayfer Design combines contemporary and industrial finishes with detailing tricks to create a spacious and interactive interior for a recently migrated family. Brighton East Interior involved cross-country collaboration between Gayfer (in Melbourne) and his Singapore-based clients who challenged him to repurpose their Victorian Californian-Bungalow into a flexible living space that met the hectic requirements of the family. The material palette used for the renovation is a mixture of industrial and contemporary elements and combines with small architectural detailing to create a series of vibrant spaces, including a new kitchen, living room and two bathrooms. In the kitchen, a polished concrete benchtop and galvanised tubing are contrasted by the warming touches of timber and pragmatic finishes like a tiled splashback and CASF Australia Corian benchtop. Western Red Cedar lining boards from Cedar Sales were chosen by Gayfer to run vertically up one of the kitchen walls as a feature and, as a little trick, also combine with concealed hinges to create an ‘invisible’ kitchen pantry. Recessed finishes like the countersunk stainless steel kitchen s...

10 Vegan-Friendly Plastic-Free Soaps for the Flu Season

Joaquin Phoenix Produces Documentary About Farm Animals and their Ability to Experience Emotions Like Pleasure, Pain and Fear EU Under Fire For Spending Millions Annually on Promoting Meat Consumption, While Preaching Climate Goals Joaquin Phoenix Produces Documentary About Farm Animals and their Ability to Experience Emotions Like Pleasure, Pain and Fear Being publicly-funded gives us a greater chance to continue providing you with high quality content. Please support us! Being publicly-funded gives us a greater chance to continue providing you with high quality content. Please support us! It’s flu season! From here on out, we’ll all be eating as much vitamin C as we can to steer clear of the dreaded illness. This also means that there will be a dramatic increase in the purchase of soap products. Why? Besides getting yourself the flu shot, the two best ways to avoid getting the flu are by covering your mouth and washing your hands. For the first, you just need a hand, but what if that hand of yours has the flu virus on it? Well, that’s why cleaning your hands with soap is essential. Soap can’t kill the flu virus, but it will dislodge it from your skin, meaning it can’t make its...

EtonShortlisted for the 2019 Stirling prize, a house at the vanguard of ‘corkitecture’ is broadening ideas

EtonShortlisted for the 2019 Stirling prize, a house at the vanguard of ‘corkitecture’ is broadening ideas of sustainable construction Fishing floats, bottle stoppers, platform soles, pinboards, coasters. The uses of cork are many and varied, but it still retains a whiff of 1970s suburbia, like avocado bathroom suites or jumbo corduroy. Yet in its way, cork is a wonder material – strong in compression (those platform soles), water-resistant and a good source of insulation. Cork is also impeccably sustainable. Bark from Quercus suber, the cork oak, is carefully stripped by hand every nine to 12 years, leaving the tree intact, unlike felling for timber. Portugal and Spain are responsible for 80% of cork production, with much of it still going to make corks for wine bottles, despite the rise of the screw top. As for cork in architecture – or “corkitecture” – the picture is more patchy. Cork has been a minor supporting player, used for flooring and wall tiles, or as an early form of insulation, sandwiched in walls. It has made the odd breakout appearance as cladding for temporary structures, such as Álvaro Siza and Eduardo Souto de Moura’s Portugal pavilion at Expo 2000 in Hanover, ...

Amazon’s Hunters is basically The Boys except with Nazi-hunting

David Weil, creator of Amazon’s Nazi-hunting thriller Hunters, says the show came out of his own family history: he contextualized the stories his Holocaust survivor grandmother told through the lens of comic book morality. The idea of World War II as a battle between grand heroes and villains is clearly expressed in Hunters — available to stream on Feb. 21 — when teenage Jewish comic-book nerd Jonah Heidelbaum (Logan Lerman of The Perks of Being a Wallflower and the Percy Jackson films) compares the Nazi-hunters he’s working with to Batman, Spider-Man and the Punisher. But the show has more in common with a different comic book series: Garth Ennis’ The Boys, which was adapted as an Amazon series last year. Both are built around ensembles rather than individual heroes, with dweeby newcomers as audience stand-ins. The Boys’ Hughie Campbell is motivated by a classic case of fridging, vowing to take vengeance on superheroes after one of the world’s most famous and powerful heroes accidentally kills his girlfriend. But by creating a wholly original work rather than adapting a nearly 15-year-old comic, Weil freed himself up to borrow tone and tropes as he sees fit, dropping and inver...

Erythritol Market Analysis of Key Players 2018-2028 | JUNGBUNZLAUER SUISSE AG, Shandong Sanyuan Biotechnology Co., Ltd

In addition, the jurisdictions including EU jurisdictions in which erythritol was regulated to be zero-kcal / g are generally recognized as safe (GRAS) as well as the Federal Food and Drug Administration (FDA). Meso-erythritol provides a response to both health and indulgence with zero calorie content. Erythritol is used as a flavor agent in the pharmaceutical industry to increase the taste of medicine. Erythritol finds use in oral care and other products in personal care. In comparison with other polyol sweeteners Meso-erythritol has the highest digestive tolerance. The demand for highly intensive sweeteners has shown steady growth over the last five years, which in the next five years will also grow at a higher rate. Consumers in emerging countries are driving the market with health consciousness and change in life style. No major constraints are obstructed on the market of erythritol; manufacturers operating in the company must respect the allowable limit to use erythritol products. At the same time, companies focus on technological innovation, upgrading equipment and improving processes to reduce costs and improve their quality. Competition in the erythritol industry will in...

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